What question did this study set out to answer?

The aim is to analyze trends in US overdose death rates by race/ethnicity and substance between 2023 and 2024.

June 4, 2026AddictionOpen Access

Charting the decline of the fourth wave: US overdose deaths by race, ethnicity and substance involvement

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Population-based study characterizes decreasing overdose death rates in the US by race and substance involvement, highlighting ongoing disparities.

The aim is to analyze trends in US overdose death rates by race/ethnicity and substance between 2023 and 2024.
Population-based analysis of national death records from the CDC WONDER platform
Examined overdose deaths from January 1999 to December 2024
Measured annual overdose deaths per 100,000 population by race/ethnicity and substance involvement.
Overall, the US overdose death rate dropped by 24.4% from 2023 to 2024
Non-Hispanic Black individuals saw a 29.3% decrease but had rates of 36.0 per 100,000, significantly higher than the national average
Non-Hispanic American Indian and Alaska Native individuals had the highest overdose death rates at 50.8 per 100,000, with a decrease of only 20.1%.

Friedman et al. (2026) studied this question.

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Population-based study characterizes decreasing overdose death rates in the US by race and substance involvement, highlighting ongoing disparities.