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This research aims to evaluate the phytochemical profiles and biological activities of six Salvia species in Turkey, validating their use in traditional medicine.

June 4, 2026PlantsOpen Access

Evaluation of the Therapeutic Potential and Safety Profile of Six Salvia Species Native to Türkiye

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Authors

NSNagehan SaltanAnadolu University FTFatmanur TunçAnadolu University MBMerve BaysalAnadolu University

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Implication

Randomized trial evaluates antioxidant, antimicrobial, and cytotoxic effects of six Salvia species, suggesting safe traditional use.

Key Points

This research aims to evaluate the phytochemical profiles and biological activities of six Salvia species in Turkey, validating their use in traditional medicine.
Phytochemical characterization using Liquid Chromatography–High-Resolution Mass Spectrometry (LC-HRMS).
Evaluation of biological potential through antioxidant (DPPH), antimicrobial (MIC), and cytotoxicity (MTT on NIH/3T3 cells) assays.
Comparative analysis of phytochemical and biological activities across six Salvia species.
S. dorystaechas showed the highest antioxidant activity with IC50 values of 0.090 mg/mL (infusion) and 0.072 mg/mL (ethanolic).
MIC values for antimicrobial activity ranged from 625 to >5000 µg/mL against bacteria and Candida spp.
S. tomentosa extract displayed the lowest cytotoxicity with an IC50 of 562.37 ± 49.50 µg/mL.

Cite This Study

Saltan et al. (2026) studied this question.

synapsesocial.com/papers/6a2117dfd499ed480b170b44 https://doi.org/10.3390/plants15111718

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Evaluation of the Therapeutic Potential and Safety Profile of Six Salvia Species Native to Türkiye

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Key Points

Cite This Study

Evaluation of the Therapeutic Potential and Safety Profile of Six Salvia Species Native to Türkiye

Discussion

Member takes

Implication

Key Points

Cite This Study

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