Independent risk factors for hospital mortality after porcine bioprosthesis implantation included mitral valve replacement (OR 5.29), tricuspid surgery (OR 3.07), and diabetes mellitus (OR 2.72).
Observational (n=808)
No
Independent risk factors for hospital mortality after porcine bioprosthesis valve replacement include mitral or tricuspid surgery, diabetes, age >70, concomitant CABG, prior cardiac surgery, and hypertension.
Odds Ratio: 5.29
OBJECTIVE: Study designed to identify characteristics of patients related to increased hospital mortality after valve replacement, assumed as risk factors. METHODS: Retrospective study including 808 patients submitted to the implant of St. Jude Biocor porcine bioprosthesis between 1994 and 2009 at Instituto de Cardiologia do Rio Grande do Sul. Primary outcome was hospital death and hospital mortality was related to demographic and surgical characteristics. Statistics include t-test, qui-square test and logistical regression analysis. RESULTS: There were 80 (9.9%) hospital deaths. Risk factors identified with univariable logistical analysis (and respective odds-ratio) were: tricuspid surgery (OR 6.11); mitral valve replacement (OR 3.98); left ventricular ejection fraction 1,4 mg/dL (OR 2.28); previous cardiac surgery (OR 2.17); systemic arterial hypertension (OR 1.93); functional class III e IV (OR 1.92); coronary bypass (OR 1.81); age > 70 years-old (OR 1.80); congestive heart failure (OR 1.73); e female gender (OR 1.68). Multivariable logistic regression for independent factors identified preponderant risk factors mitral valve replacement (OR 5,29); tricuspid surgery (OR 3.07); diabetes mellitus (OR 2.72); age > 70 years-old (OR 2.62); coronary bypass (OR 2.43); previous cardiac surgery (OR 1.82); e systemic arterial hypertension (OR 1.79). CONCLUSIONS: Mortality rate is within values found in literature. Identification of risk factors could contribute to changes in surgical indication and medical management in order to reduce hospital mortality.
Fornari et al. (Sun,) conducted a observational in Valve replacement (n=808). Clinical and surgical risk factors (e.g., mitral valve replacement) vs. Absence of respective risk factors was evaluated on Hospital death (OR 5.29). Independent risk factors for hospital mortality after porcine bioprosthesis implantation included mitral valve replacement (OR 5.29), tricuspid surgery (OR 3.07), and diabetes mellitus (OR 2.72).