Key result
Age >70 years did not increase overall morbidity and mortality following aortic valve replacement compared to age <70 years, with older patients achieving 75% survival at 5 years.
Why the study?
Does age >70 years increase operative morbidity and mortality following aortic valve replacement compared to age <70 years?
Cohort (n=306)
Does age >70 years increase operative morbidity and mortality following aortic valve replacement compared to age <70 years?
Answers are grounded in this paper and cite their sources.
Aortic valve replacement in patients over 70 years of age is safe with long-term survival comparable to age- and sex-matched controls from the general population.
Retrospective analysis of 306 patients following aortic valve replacement (AVR) was carried out between 1985-89. Patients were divided into two groups: group 1 patients were less than 70 years of age and group 2 were greater than 70 years of age. The multivariant analysis of risk factors showed the only increased risk for surgery was the NYHA class IV in either group. There was no overall difference in morbidity and mortality. The actuarial survival rate for group 2 patients was 95% at 1 year and 75% at 5 years. This was not different when compared for death in age- and sex-matched controls from the general population. AVR in the elderly is safe, the long-term result is good and it remains the treatment of choice unless there is an absolute contraindication.
No takes yet. Share an insight, caveat, or question.
BERGUS et al. (1992) conducted a cohort in Aortic valve disease requiring replacement (n=306). Age >70 years vs. Age <70 years was evaluated on Operative morbidity and mortality. Age >70 years did not increase overall morbidity and mortality following aortic valve replacement compared to age <70 years, with older patients achieving 75% survival at 5 years.
Synapse has enriched 10 related papers. Consider them for comparative context: