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An antigenic analysis has been performed of 48 strains of Staphylococcus epidermidis , mostly belonging to biochemical type 1. Rabbit preimmune sera were found to contain shared natural antibodies in low titres against S. epidermidis and S. aureus . Cross‐agglutination and absorption experiments showed that the two species share antigens to a considerable degree. After removal of the shared antibodies by absorption, several specific S. epidermidis antibodies were registered. Glycerol α‐glucosyl teichoic acid (polysaccharide B) was demonstrated in 67 per cent of the S. epidermidis strains on double diffusion in agar gel. An unknown precipitinogen was demonstrated in 37 strains. Serologic examination is recommended in the evaluation of coagulase‐negative staphylococci isolated from infections.
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Aasen et al. (1971) studied this question.
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