Population
Excised ventricular segments from Hamburger/Hamilton stage-16 or stage-18 embryonic chicks
Design
Preclinical
Authors
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Nonlinear embryonic myocardial properties warrant no clinical change; leaves open their role in regulating cardiac morphogenesis.
This study provides the first stress-strain measurements of embryonic cardiovascular tissue, revealing nonlinear behavior and large hysteresis loops, which may help identify biomechanical factors regulating cardiac growth and morphogenesis.
Miller et al. (1997) studied this question.
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