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Maturation‐promoting factor (MPF) has been known to be produced in the cytoplasm of starfish and amphibian oocytes, where it triggers meiotic maturation. Cytoplasm obtained from maturing oocytes of either mouse or surf clam was found to induce maturation when injected into immature starfish oocytes. These facts suggest that MPF is also produced in oocytes of the mouse and surf clam and that MPF acts in a general, nonspecific manner in mammals, echinoderms, and molluscs.
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Kishimoto et al. (1984) studied this question.
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