Key result
Lower GFR is linked to ~6% higher all-cause mortality per 10-unit drop in LV dysfunction.
Why the study?
Do reduced kidney function and anemia increase the risk of all-cause mortality in patients with left ventricular dysfunction?
Cohort
Do reduced kidney function and anemia increase the risk of all-cause mortality in patients with left ventricular dysfunction?
Hazard Ratio: 1.064 (95% CI 1.033–1.096)
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Decreased kidney function and anemia are independent and interacting risk factors for all-cause mortality in patients with left ventricular dysfunction.
Al‐Ahmad et al. (2001) conducted a cohort in Left ventricular (LV) dysfunction. Reduced kidney function (lower GFR) and lower hematocrit vs. Higher GFR and hematocrit was evaluated on All-cause mortality (HR 1.064, 95% CI 1.033-1.096). Lower GFR (HR 1.064 per 10 ml/min/1.73 m2 decrease) and lower hematocrit (HR 1.027 per 1% decrease) were associated with increased all-cause mortality in patients with LV dysfunction.
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