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August 15, 1995Proceedings of the National Academy of SciencesOpen Access

Tonic stimulation of renin gene expression by nitric oxide is counteracted by tonic inhibition through angiotensin II.

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Authors

KSK. Th. SchrickerUniversitätsklinikum Erlangen IHIvan HegyiUniversity of Bern MHMark HamannJames Cook University

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Implication

Rat data implicate prostaglandins/NO in ACEI/ARB renin stimulation; leaves open human mechanistic relevance.

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Cite This Study

Schricker et al. (1995) studied this question.

synapsesocial.com/papers/6a214812c4e60624665adec6 https://doi.org/10.1073/pnas.92.17.8006

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Reciprocal feedback regulation of kidney angiotensinogen and renin mRNA expressions by angiotensin II1992 · 133 citations
2Angiotensin II regulates renin gene expression1990 · 96 citations
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5Influence of sodium diet on L-NAME effects on renin release and renal vasoconstriction1994 · 33 citations