Why the study?
Does the uremic solute-AHR-TF axis associate with thrombosis after vascular injury in patients with CKD?
Does the uremic solute-AHR-TF axis associate with thrombosis after vascular injury in patients with CKD?
The uremic solute-AHR-TF axis, specifically driven by indoxyl sulfate and kynurenine, is associated with an increased risk of thrombosis after vascular injury in patients with chronic kidney disease.
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The uremic solute-AHR-TF axis was associated with AV thrombosis in CKD; hypothesis-generating and requires prospective validation before clinical consideration.
Kolachalama et al. (2018) studied this question.
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