Key result
Home-based VR exercise cuts depression scores ~3 points vs. standard brochure in cardiac rehab.
Why the study?
Exercise is essential in cardiac rehabilitation after open-heart surgery, and VR-based aerobic exercises are used in this setting, but their effects on depression and quality of life in community-dwelling post-surgery patients required evaluation.
Does an 8-week home-based VR aerobic exercise program improve depression and quality of life in patients undergoing phase II cardiac rehabilitation after open-heart surgery?
RCT (n=47)
Single-blind
Computer-generated simple random sequence with 1:1 allocation
No
Does an 8-week home-based VR aerobic exercise program improve depression and quality of life in patients undergoing phase II cardiac rehabilitation after open-heart surgery?
Mean Difference: -2.88
Absolute Event Rate: 3.17% vs 6.04%
p-value: p=0.049
An 8-week home-based virtual reality exercise program significantly improved depression scores compared to standard written exercise prescriptions in patients undergoing phase II cardiac rehabilitation after open-heart surgery.
Reduces depressive symptoms during phase II cardiac rehabilitation after open-heart surgery; extends exercise benefits to home-based VR delivery in this population.
Background: Exercise is an integral component of cardiac rehabilitation after open-heart surgery in both hospital and community settings, and such programs are designed to reduce adverse physical and mental health outcomes in patients undergoing cardiac surgery. Virtual reality (VR)-based aerobic exercises are used for cardiac rehabilitation. We aimed to analyze the effects of an eight-week home-based phase II cardiac rehabilitation program performed in VR on depression and quality of life (QOL) in community-dwelling individuals who underwent open-heart surgery. Methods: A randomized controlled trial was conducted, and 49 patients who underwent elective open-heart surgery were assigned to either the VR group (n=24) or the control group. Members of the control group received a paper booklet (n=25) during phase II cardiac rehabilitation. Depression and SF-36 scores were assessed at baseline and at eight weeks. Results: The VR group showed a significant decrease in depression after eight weeks, compared to the control group (D-1.75, p=.003, n2p=0.175). The SF-36 showed no significant differences between the VR and control groups. Conclusions: A home-based VR exercise program has applications in phase II cardiac rehabilitation for open-heart surgery by reducing depression but not QOL. Therefore, integrating VR exercise into cardiac rehabilitation programs may offer a novel strategy to address mental health challenges.
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Yuenyongchaiwat et al. (2026) conducted an RCT in Phase II cardiac rehabilitation after open-heart surgery (n=47). Virtual reality (VR)-based aerobic exercise program vs. Standard care (exercise prescription brochure) was evaluated on Depression (assessed via PHQ-9 score) (MD -2.88, p=0.049). An 8-week home-based virtual reality aerobic exercise program significantly reduced depression scores (MD -2.88) compared to a standard exercise brochure in patients undergoing phase II cardiac rehabilitation.
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