Key result
Inspiration reduced left ventricular stroke volume by 7% in normal patients (P<0.01) and by 25% in patients with airway obstruction (P<0.001).
Why the study?
Does inspiration affect left ventricular stroke volume in normal patients and those with airway obstruction or pericardial tamponade?
Observational (n=22)
Does inspiration affect left ventricular stroke volume in normal patients and those with airway obstruction or pericardial tamponade?
p-value: p=<0.01
Inspiration causes an immediate fall in left ventricular stroke volume, likely due to reduced left ventricular filling, with exaggerated effects in patients with airway obstruction.
No takes yet. Share an insight, caveat, or question.
May exaggerate inspiratory LV effects in obstruction; leaves open relevance to tamponade and need for prospective studies.
Ruskin et al. (1973) conducted an observational in Normal, airway obstruction, pericardial tamponade (n=22). Inspiration was evaluated on Change in left ventricular stroke volume, systolic pressure, and pulse pressure (p=<0.01). Inspiration reduced left ventricular stroke volume by 7% in normal patients (P<0.01) and by 25% in patients with airway obstruction (P<0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: