Key result
Intravenous rt-PA was administered safely and effectively with no complications in a young patient presenting with acute ischemic stroke due to cardiac myxoma.
Why the study?
There have been debates about whether it is safe to use recombinant tissue plasminogen activator (rt-PA) in patients with cardiac myxoma presenting with ischemic stroke.
Does intravenous rt-PA safely treat acute ischemic stroke in patients with cardiac myxoma?
Case Report (n=1)
Does intravenous rt-PA safely treat acute ischemic stroke in patients with cardiac myxoma?
Intravenous rt-PA can be safely administered in patients presenting with acute ischemic stroke due to cardiac myxoma, though efficacy may vary for tumor emboli.
Single case supports potential IV rt-PA safety in myxoma stroke; leaves open need for systematic evaluation.
Background: Myxoma may cause systemic embolization and frequently presents as ischemic stroke. Case Presentation: There have been debates about whether it is safe to use recombinant tissue plasminogen activator (rt-PA) in patients with cardiac myxoma who referred with ischemic stroke to the hospital's emergency. Results: The patient was a young case of atrial myxoma with initial presentation of acute cerebral infarction symptoms who was treated with intravenous rt-PA with no complications. Conclusion: The case provides an evidence of the efficacy and safety of intravenous rt-PA in cases of cardiac myxoma. However, we cannot always expect thrombolytic therapy to be effective, especially in tumor emboli.
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Esmaeili et al. (2020) conducted a case report in Acute Ischemic Stroke Due to Cardiac Myxoma (n=1). Intravenous recombinant tissue plasminogen activator (rt-PA) was evaluated on Efficacy and safety (complications). Intravenous rt-PA was administered safely and effectively with no complications in a young patient presenting with acute ischemic stroke due to cardiac myxoma.
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