Key result
Surgical resection of cardiac myxoma is associated with a low complication rate, a 30-day mortality of up to 10%, and a long-term recurrence rate of approximately 5%.
Why the study?
To summarize available data on cardiac myxoma, particularly regarding issues relating to diagnosis and treatment.
What are the clinical characteristics, diagnostic modalities, and surgical outcomes of patients with cardiac myxoma?
What are the clinical characteristics, diagnostic modalities, and surgical outcomes of patients with cardiac myxoma?
Surgical resection of cardiac myxoma is safe and effective, with low 30-day mortality and a recurrence rate of approximately 5%, necessitating long-term echocardiographic follow-up.
May warrant long-term echocardiographic surveillance after resection; leaves open optimal protocols in prospective studies.
Cardiac myxoma is the most common benign cardiac tumor. It is located in the left atrium and typically arises from the foramen ovale in approximately 75% of the general patient population, in the right atrium in 23%, and in the ventricles in only 2%. Symptoms depend on its size, mobility, and relation to surrounding cardiac structures. Neurological complications resulting from cardiac myxoma are seen in 20% to 25% of patients. Molecular genetic studies show that the condition can be inherited in Carney complex due to mutations of the PRKAR1A gene. Cardiac myxoma resection is a cardiac surgery with a low complication rate and the 30‑day mortality of up to 10%. Recurrence may be observed months or years after surgery, and its rate is approximately 5%. Long‑term follow‑up with transthoracic echocardiography is needed in all patients after tumor resection. This review summarizes the available data on cardiac myxoma and, in particular, issues relating to diagnosis and treatment.
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Samanidis et al. (2020) conducted a review in Cardiac myxoma (n=2,205). Surgical resection was evaluated on 30-day mortality and recurrence rate. Surgical resection of cardiac myxoma is associated with a low complication rate, a 30-day mortality of up to 10%, and a long-term recurrence rate of approximately 5%.
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