Why the study?
Does an increase in heart rate affect the uncorrected PEP/LVET ratio in normal individuals?
Population
26 normal volunteers
Comparison
Increase in heart rate by either intravenous… vs Baseline (lower heart rate)
Design
Other
Authors
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Uncorrected PEP/LVET may confound contractility assessment at higher rates; leaves open validation of rate-correction in prospective studies.
Does an increase in heart rate affect the uncorrected PEP/LVET ratio in normal individuals?
The PEP/LVET ratio, used to express left ventricular contractility, is significantly influenced by heart rate and should be corrected using the derived regression equation.
Cokkinos et al. (1976) studied this question.
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