Key result
Digitalis exhibits novel mechanisms of action, including intracellular signaling and interactions with specific Na-K-ATPase isoforms, which may inform future therapeutic interventions for heart failure.
Design
Review
Authors
Loading...
Digitalis use in heart failure remains unchanged; leaves open isoform-specific targeting for future trials.
Recent observations suggest digitalis has novel intracellular and signaling effects beyond NKA inhibition, which may inform future therapeutic interventions for heart failure.
Wasserstrom et al. (2005) conducted a review in Heart failure. Digitalis was evaluated. Digitalis exhibits novel mechanisms of action, including intracellular signaling and interactions with specific Na-K-ATPase isoforms, which may inform future therapeutic interventions for heart failure.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: