Why the study?
Are there sex differences in pain-related cerebral processing as measured by BOLD signal change during noxious heat stimuli?
Population
28 healthy volunteers (17 women, 11 men)
Comparison
Noxious heat stimuli applied to the dorsum of… vs Men vs Women
Design
Cross-sectional
Authors
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May not alter sex-specific pain assessment; leaves open whether BOLD differences drive clinical outcomes.
Are there sex differences in pain-related cerebral processing as measured by BOLD signal change during noxious heat stimuli?
Women demonstrate lower BOLD signal amplitude in specific cerebral regions compared to men during equivalent pain perception, suggesting sex differences in pain-related cerebral processing.
Moulton et al. (2006) studied this question.
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