May 9, 2002New England Journal of Medicine163 citations
View Full PaperAspirin for Primary Prevention of Coronary Events
Key Result
Aspirin for primary prevention of myocardial infarction is discussed in the context of a 45-year-old asymptomatic man with hyperlipidemia and a family history of premature heart disease.
Study Design
Type
Case Report (n=1)
PICO
P
Population
A 45-year-old asymptomatic man with a strong family history of premature heart disease and hyperlipidemia being evaluated for primary prevention with aspirin.
I
Intervention / Comparator
Aspirin
O
Primary Outcome
Risk of myocardial infarction
Abstract
A 45-year-old man with a strong family history of premature heart disease has no symptoms of coronary disease and a normal electrocardiogram. His fasting level of total cholesterol is 225 mg per deciliter, the low-density lipoprotein cholesterol level is 160 mg per deciliter, and the high-density lipoprotein cholesterol level is 35 mg per deciliter. He has no history of hypertension and does not smoke cigarettes. Should he be advised to take aspirin to reduce his risk of myocardial infarction?