Why the study?
Does sympathectomy alter arthritis severity and cytokine profiles in mice with type II collagen-induced arthritis?
Does sympathectomy alter arthritis severity and cytokine profiles in mice with type II collagen-induced arthritis?
The sympathetic nervous system exerts a bimodal, time-dependent immune-modulating effect in collagen-induced arthritis, promoting early inflammation but suppressing late chronic inflammation.
No takes yet. Share an insight, caveat, or question.
Should not yet change arthritis management; leaves open time-dependent sympathetic modulation for targeted human studies.
Härle et al. (2005) studied this question.
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