Key result
Chronic kidney disease is a recognized risk factor for cognitive impairment and dementia, and while physical exercise may offer short-term cognitive benefits, its long-term efficacy remains unclear.
Why the study?
The number of aging patients with both CKD and dementia is increasing, making clinical management challenging and worsening prognoses, which highlights the urgency of developing effective countermeasures.
Does physical exercise therapy prevent cognitive decline in patients with chronic kidney disease?
Does physical exercise therapy prevent cognitive decline in patients with chronic kidney disease?
Physical exercise shows potential for short-term cognitive benefits in CKD patients, but evidence for long-term dementia prevention is currently lacking.
Physical exercise may yield short-term cognitive benefits in CKD; leaves open long-term dementia prevention.
Chronic kidney disease (CKD) is a recognized risk factor for cognitive impairment and dementia. Unfortunately, the number of patients with both CKD and dementia has been steadily increasing with the aging patient population. Therapeutic management and clinical decision-making become more challenging in patients with dementia who often experience worsening prognoses, highlighting the urgency of developing effective countermeasures. This review explores available research on the epidemiology, contributing factors, mechanisms, and outcomes of cognitive impairment and dementia in patients with CKD while outlining the impact of exercise therapy on cognitive function.
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Yuhei Otobe (2024) conducted a review in Chronic kidney disease and cognitive impairment. Physical exercise was evaluated. Chronic kidney disease is a recognized risk factor for cognitive impairment and dementia, and while physical exercise may offer short-term cognitive benefits, its long-term efficacy remains unclear.
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