Key result
High atherogenic index of plasma is linked to ~3.2-fold higher odds of obesity.
Why the study?
Atherogenic index of plasma is associated with cardiovascular diseases and obesity, but its relationship with obesity among Taiwanese hospital employees required investigation.
Is the atherogenic index of plasma associated with obesity among adults?
Cross-Sectional (n=1,312)
No
Is the atherogenic index of plasma associated with obesity among adults?
Odds Ratio: 3.22
p-value: p=<0.001
Atherogenic index of plasma is strongly associated with obesity and metabolic syndrome components in Taiwanese adults.
High AIP was associated with 3.22-fold obesity odds; hypothesis-generating for risk stratification and needs prospective validation.
Atherogenic index of plasma (AIP), a novel biomarker, is associated with cardiovascular diseases and obesity. The main aim of this study was to investigate the relationship between AIP and obesity among Taiwanese hospital employees. A total of 1312 subjects with an average age of 42.39 years were enrolled in this cross-sectional study. AIP was calculated as log10 (TG/HDL-C). All subjects were divided into three groups according to AIP tertiles. Chi-square test, independent t-test and one-way ANOVA were used to compare the demographic and clinical lab characteristics of the three groups. Multivariate logistic regression analysis was used to assess the relationship between AIP and obesity. The results showed that subjects with obesity or with high AIP levels exhibited significant differences in systolic blood pressure, diastolic blood pressure, waist circumference, alanine aminotransferase, fasting plasma glucose, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglycerides and prevalence of diabetes mellitus, hypertension, hyperlipidemia and metabolic syndrome. In addition, age and total cholesterol were increased in the high AIP group. Increased AIP levels were strongly associated with obesity.
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Zhang et al. (2022) conducted a cross-sectional in Obesity (n=1,312). High atherogenic index of plasma (AIP) vs. Low atherogenic index of plasma (AIP) was evaluated on Obesity (BMI ≥ 27 kg/m²) (OR 3.22, p=<0.001). High levels of atherogenic index of plasma (AIP) were independently associated with a 3.22-fold increased odds of obesity compared to low AIP levels among Taiwanese hospital employees.
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