Key result
Blocked atrial bigeminy mimicking sinus bradycardia causes marked asymptomatic bradycardia unresponsive to flecainide and amiodarone.
Why the study?
The diagnosis of blocked atrial bigeminy can be challenging and easily misinterpreted as sinus bradycardia or sinus exit block, potentially leading to unnecessary pacemaker implantation.
Case Report (n=1)
Blocked atrial bigeminy is a rare cause of bradycardia that can mimic sinus bradycardia or exit block, and accurate ECG recognition is crucial to avoid unnecessary pacemaker implantation.
ECG recognition of blocked atrial bigeminy may avert unnecessary pacing; this case leaves open its prevalence in bradycardia differentials.
The diagnosis of blocked atrial bigeminy may be challenging. It can easily be misinterpreted as sinus bradycardia or sinus exit block leading to unnecessary pacemaker implantation. We report a case of frequent blocked premature atrial contractions leading to episodes of marked bradycardia. A 66-year-old man disturbed with low pulse (42 bpm) measured by an automated blood pressure monitor sought medical attention. The patient also had untreated grade I arterial hypertension. Ambulatory ECG monitoring was performed and very frequent blocked premature atrial contractions were seen. The P wave of the atrial premature atrial contractions was always superimposed on the ST segment or T wave simulating a bifid T wave. Blocked atrial quadrigeminy, blocked atrial trigeminy, and blocked atrial bigeminy were observed. The minimum heart rate associated with blocked atrial bigeminy was 37 bpm. There were multiple episodes of regular ventricular rhythm during blocked atrial bigeminy. NT-proBNP concentration was within normal limits. Echocardiography showed only mild left ventricular hypertrophy, mild left atrial dilation and type I diastolic dysfunction. Therapy with flecainide and amiodarone separately was not effective. Option of radiofrequency catheter ablation was discussed with the patient, but was not accepted due to procedural risks and absence of severe symptoms related to blocked PACs. The patient was reassured and regular follow-up was recommended. The target values of blood pressure were achieved with candesartan at a dose of 32 mg. Thus, blocked atrial bigeminy is a rare cause of bradycardia with a regular ventricular rhythm. Recognition of the P wave superimposed on the ST segment or the T wave may be a clue for a correct diagnosis. Physicians should be aware of this condition to avoid unnecessary pacemaker implantation.
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Skakun et al. (2025) conducted a case report in Bradycardia due to blocked atrial bigeminy (n=1). Blocked atrial bigeminy was evaluated on Heart rate and rhythm. Blocked atrial bigeminy mimicking sinus bradycardia caused marked asymptomatic bradycardia in a 66-year-old man and was unresponsive to flecainide and amiodarone.
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