Why the study?
Does male sex increase the risk of recurrent venous thrombosis compared to female sex in thrombophilic families?
Does male sex increase the risk of recurrent venous thrombosis compared to female sex in thrombophilic families?
The higher lifetime risk of recurrent venous thrombosis in men compared to women in thrombophilic families is largely explained by women's younger age at first event due to hormonal risk factors and longer intervals between provoked first episodes and recurrence.
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Sex differences in recurrence risk may reflect provoked events in women; leaves open independent male risk after unprovoked events in thrombophilic families.
Lijfering et al. (2009) studied this question.
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