Key result
High-performance male athletes had significantly greater indexed cellular mass compared to low-performance athletes (60.7 vs 48.6 g/m2; P<0.001), while extracellular mass remained constant.
Why the study?
Does athletic training increase myocardial cellular mass rather than extracellular mass in males?
Population
45 males (30 athletes and 15 sedentary age-matched healthy controls)
Comparison
Athletic training vs Sedentary age-matched healthy controls
Design
Cross-sectional
Authors
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May aid CMR differentiation of athlete's heart from cardiomyopathy in males; leaves open causality and effects in females.
Cross-Sectional (n=45)
Does athletic training increase myocardial cellular mass rather than extracellular mass in males?
Absolute Event Rate: 60.7% vs 48.6%
p-value: p=<0.001
Athletic left ventricular hypertrophy is driven by an expansion of the cellular compartment rather than the extracellular matrix, which may help differentiate athlete's heart from cardiomyopathy using CMR.
McDiarmid et al. (2016) conducted a cross-sectional in Athlete's heart (n=45). High-performance athletic training vs. Low-performance athletic training / Sedentary controls was evaluated on Indexed cellular mass (g/m2) (p=<0.001). High-performance male athletes had significantly greater indexed cellular mass compared to low-performance athletes (60.7 vs 48.6 g/m2; P<0.001), while extracellular mass remained constant.
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