Key result
CKD prescriptions show frequent drug-drug interactions, with ~69% classified as moderate severity.
Why the study?
The study was conducted to review drug-drug interactions among CKD patients.
Observational (n=150)
Yes
Drug-drug interactions are highly prevalent in CKD patients, with moderate interactions being the most common, emphasizing the need for careful medication review.
Supports DDI screening in CKD; leaves open hypertension's independent role in larger prospective studies.
Aim: To review Drug-Drug interactions among CKD patients. Methodology: A concurrent conciliation study was performed on CKD patients with drug-drug interactions admitted in and around tertiary government and corporate hospitals, Visakhapatnam, Andhra Pradesh, India. Information regarding gender, and variety of drug interactions as mild, moderate, and major were recorded in the standard questionnaire. Result: Overall 150 prescriptions were included after excluding missing data. The impact of concomitant disease in causing drug-drug interactions in 150 prescriptions them were Hypertension -35%, Diabetes Mellitus-19%, Hyperlipidemia-8%, Asthma- 7%, Seizures- 6%, Thyroid -5%, Congestive Heart Failure- 1%. Total of 201 interactions were revealed of which 15 were major interactions, 139 were moderate interactions, 47 were minor interactions. Conclusion: By assessing the above data it absolutely was concluded that the patient should possess sound knowledge of drug interactions before employing a selected drug or two or more drugs at the identical time so as to possess identical medication.
No takes yet. Share an insight, caveat, or question.
Rushinaidu et al. (2022) conducted an observational in Chronic Kidney Disease (n=150). Polypharmacy and specific drug combinations was evaluated on Prevalence and severity of drug-drug interactions (major, moderate, minor). Among 150 chronic kidney disease patient prescriptions, a total of 201 drug-drug interactions were identified, comprising 15 major, 139 moderate, and 47 minor interactions.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: