What does this research mean for the field?

Ex vivo antigen-loaded dendritic cell vaccines represent a viable and encouraging platform for preventing infectious diseases, including HIV/AIDS, hepatitis B, Herpes simplex, and COVID-19. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

November 21, 2025Human Vaccines & Immunotherapeutics1 citationsOpen Access

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A review of vaccinology and ex vivo antigen-loaded dendritic cells: A different approach to infectious disease vaccines

RDRobert O. DillmanAllergan (Ireland)GNGabriel I. NistorAllergan (Ireland)HKHans S. KeirsteadCalifornia Institute for Regenerative Medicine

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Abstract

antigen-presenting cells to migrate to the injection site to load antigens. DC vaccines against HIV/AIDS, hepatitis B, and Herpes simplex have yielded encouraging results. During the SARS-CoV-2 COVID-19 pandemic, DC vaccines emerged as a viable vaccine platform against infectious diseases.

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Dillman et al. (Fri,) studied this question.

synapsesocial.com/papers/6a219cb3cdf8429e7e5fdd51 https://doi.org/https://doi.org/10.1080/21645515.2025.2588861

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