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BACKGROUND: The majority of patients with Alzheimer's disease live outside institutions and there is considerable serious psychological morbidity among their carers. AIMS: To evaluate whether family intervention reduces the subjective burden of care in carers of patients with Alzheimer's disease and produces clinical benefits in the patients. METHOD: A prospective single-blind randomised controlled trial with three-month follow-up in which the experimental group received family intervention and was compared with two control groups. RESULTS: There were significant reductions in distress and depression in the intervention group compared with control groups at post-treatment and follow-up. There were significant reductions in behavioural disturbance at post-treatment and an increase in activities at three months in patients in the intervention group. Based on an improvement on the General Health Questionnaire resulting in a carer converting from a case to a non-case, the number to treat was three immediately post-treatment and two at follow-up. CONCLUSIONS: Family intervention can have significant benefits in carers of patients with Alzheimer's disease and has a positive impact on patient behaviour.
Marriott et al. (Thu,) studied this question.