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To evaluate a new chemical shift imaging technique utilizing SSFP methods for phosphorus-31 imaging in human muscles.

Fast ³¹P chemical shift imaging using SSFP methods

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To evaluate a new chemical shift imaging technique utilizing SSFP methods for phosphorus-31 imaging in human muscles.
Implemented a chemical shift imaging technique based on SSFP signal formation.
Measured steady-state signal in human muscles at 2 T.
Compared SNR of PCr signal to a FLASH-based CSI method.
Achieved approximately 4-5 times higher SNR for phosphocreatine than FLASH-based CSI.
Demonstrated fast CSI acquisitions with subcentimeter resolution.
Successfully measured steady-state signal mainly consisting of phosphocreatine.

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Randomized trial demonstrates improved chemical shift imaging in human muscles, suggesting enhanced imaging techniques.

Speck et al. (2002) studied this question.

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