Key result
Alterations in autonomic regulation in obesity are determined by causal factors such as overeating, genetic make-up, age, and the duration of obesity in rat models.
This review highlights that autonomic dysfunction in obesity is multifactorial, driven by overeating, genetics, age, and obesity duration.
Does not support practice changes from rat data; leaves open human validation of multifactorial autonomic drivers in obesity.
Obesity is often accompanied by alterations in both sympathetic and parasympathetic autonomic functions. The present paper summarizes the results of a number of studies designed to investigate autonomic functioning in normal, genetically, and experimentally obese rats. Particular emphasis is given to autonomic functioning and dysfunctioning in relation to the processes that are involved in the regulation of peripheral energy substrate homeostasis. It is concluded that alterations in autonomic regulation in obesity are determined by causal factors such as overeating, genetic make-up, age and/or the duration of obesity.
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Scheurink et al. (1995) conducted a review in Obesity. Obesity vs. Normal weight was evaluated. Alterations in autonomic regulation in obesity are determined by causal factors such as overeating, genetic make-up, age, and the duration of obesity in rat models.
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