Key result
Sympathetic nervous system activation increases energy expenditure and decreases food intake, while parasympathetic activity can paradoxically enhance energy consumption in obesity.
This review highlights the critical role of the autonomic nervous system in regulating energy balance, suggesting that altered sympathetic and parasympathetic activity contribute to the pathophysiology of obesity.
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May inform autonomic-targeted obesity research; leaves open causal validation and clinical translation.
Messina et al. (2013) conducted a review in Obesity. Autonomic nervous system was evaluated. Sympathetic nervous system activation increases energy expenditure and decreases food intake, while parasympathetic activity can paradoxically enhance energy consumption in obesity.
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