Key result
A dynamic simulation using an electronic model showed an approximately linear relationship between diastolic arterial pressure and flow with a zero flow pressure intercept of approximately 40 mmHg.
A dynamic simulation of the coronary vessel demonstrates an approximately linear relationship between diastolic arterial pressure and flow, with a zero flow pressure intercept of ~40 mmHg, consistent with animal models.
Does not warrant changes in coronary assessment; extends animal data via simulation but leaves open human validation.
A dynamic simulation was performed in order to study the high zero-flow pressure phenomenon by using an electronic model of the coronary vessel. The objective of this study was to establish a relationship between the diastolic arterial pressure and diastolic arterial flow. The simulated study showed that this relationship is approximately linear with a zero flow pressure intercept of approximately 40 mmHg. This result is consistent with the results obtained in animal experimentation conducted by others.
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Kosugi et al. (2001) studied High zero-flow pressure phenomenon in coronary circulation. Dynamic simulation using an electronic model of the coronary vessel was evaluated on Relationship between diastolic arterial pressure and diastolic arterial flow. A dynamic simulation using an electronic model showed an approximately linear relationship between diastolic arterial pressure and flow with a zero flow pressure intercept of approximately 40 mmHg.