Key result
Unchecked disease-related stress and hypertrophic remodeling in ventricular pressure overload become maladaptive and predispose to cardiovascular morbidity and mortality.
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Discusses the concept that inhibiting hypertrophic growth and maladaptive remodeling in ventricular pressure overload may be a beneficial therapeutic strategy.
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Schiattarella et al. (2015) conducted a review in Ventricular pressure overload and hypertrophy. Inhibition of hypertrophy was evaluated. Unchecked disease-related stress and hypertrophic remodeling in ventricular pressure overload become maladaptive and predispose to cardiovascular morbidity and mortality.
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