Answers are grounded in this paper and cite their sources.
The template activity of DNA with calf thymus DNA polymerase has been studied in sections of fixed brain, liver, and heart tissues from young and senescent mice. The enzyme catalyzed greater incorporation of deoxyribonucleotide monophosphates into nuclei of old mouse neurons, astrocytes, Kupffer cells, and heart muscle fibers. The results are interpreted as the accumulation of DNA strand breaks with aging.
No takes yet. Share an insight, caveat, or question.
Price et al. (1971) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: