Programmed atrial stimulation and overdrive atrial pacing in 18 patients with atrial flutter demonstrated cycle length responses and termination patterns suggesting a re-entry circuit mechanism.
What is the electrophysiological response of atrial flutter to programmed atrial stimulation and overdrive atrial pacing in humans?
Programmed atrial stimulation and overdrive pacing demonstrate electrophysiological responses consistent with a re-entry circuit mechanism for atrial flutter in humans.
The response of atrial flutter (AF) to programmed atrial stimulation (PAS) (13 cases) and overdrive atrial pacing (OAP) ws studied in a total of 18 patients. During PAS the return cycle was equal to the basic cycle of AF in six patients, shorter in one patient, and slightly longer in six; it was never compensatory. ATrial flutter terminated in two patients by PAS and by OAP in three. In 4 patients, PAS resulted in an acceleration of the AF rate, followed by spontaneous interruption within 2 seconds. In the remaining patients, the stimulation either converted the AF into an uncommon type of AF (two patients) or into atrial fibrillation that was followed by spontaneous return to sinus rhythm. In two patients it was possible to reproduce the AF with PAS; in one of the patients another type of AF was induced. Some of the data observed suggest a re-entry circuit as the electrogenetic mechanism responsible for AF in man.
Disertori et al. (Sun,) conducted a other in Atrial flutter (n=18). Programmed atrial stimulation and overdrive atrial pacing was evaluated on Response of atrial flutter to stimulation (termination and cycle length changes). Programmed atrial stimulation and overdrive atrial pacing in 18 patients with atrial flutter demonstrated cycle length responses and termination patterns suggesting a re-entry circuit mechanism.