Key result
Intermittent, but not continuous, hypoxia induced ventilatory long-term facilitation (increased VE and VE/VCO2) in unanesthetized rats 60 minutes post-exposure.
Why the study?
Does intermittent hypoxia induce ventilatory long-term facilitation in unanesthetized rats compared to continuous hypoxia?
Does intermittent hypoxia induce ventilatory long-term facilitation in unanesthetized rats compared to continuous hypoxia?
Unanesthetized rats exhibit ventilatory long-term facilitation after intermittent, but not continuous, hypoxia.
No takes yet. Share an insight, caveat, or question.
Should not inform clinical hypoxia protocols; leaves open translation of ventilatory plasticity to humans.
Olson et al. (2001) studied this question. Intermittent hypoxia vs. Continuous hypoxia and baseline was evaluated on Minute ventilation (VE) and VE/VCO2 60 minutes after exposure. Intermittent, but not continuous, hypoxia induced ventilatory long-term facilitation (increased VE and VE/VCO2) in unanesthetized rats 60 minutes post-exposure.
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