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Abstract A technique suitable for quantitative measurements of circulatory and metabolic processes in subcutaneous adipose tissue in vivo is described. Electrical stimulation of sympathetic nerves to the adipose tissue induces a net release of FFA as well as vasoconstriction. A maximal release rate of FFA seems to be obtained with a stimulus frequency of about 3/sec. The vasoconstrictor reaction following sympathetic nerve stimulation supresses the release rate of FFA. This is especially true following stimulation with higher frequencies of 5/sec, or more. Provided the stimulation frequencies are within the physiological range the stimulation period must be 2 min, or more, in order to produce a rise in the release rate of FFA. The data indicate that sympathetic nerves to subcutaneous adipose tissue have the ability to mobilize energy for the organism within a few minutes.
Sune Rosell (1966) studied this question.