Key result
Anterior myocardial infarction was associated with a significant decrease in systolic left ventricular twist compared to controls (P<0.01), which correlated with global LV function (P<0.001).
Why the study?
Does acute anterior myocardial infarction decrease systolic left ventricular twist as measured by color tissue Doppler echocardiography?
Case-Control (n=54)
Does acute anterior myocardial infarction decrease systolic left ventricular twist as measured by color tissue Doppler echocardiography?
Acute anterior myocardial infarction decreases systolic LV twist, which correlates with global LV function and can be effectively assessed using color tissue Doppler echocardiography.
Answers are grounded in this paper and cite their sources.
May support twist assessment post-anterior MI; leaves open prospective validation of color tissue Doppler for risk stratification.
We sought to characterize the alterations of left ventricular (LV) twist after acute myocardial infarction in humans and to study their relationship to usual parameters of LV function. Systolic LV twist was measured by color tissue Doppler echocardiography (TDE) in 34 patients after anterior myocardial infarction and in 20 controls. In a subset of controls and patients, the assessment of LV twist by TDE was validated against magnetic resonance (MR) tissue tagging with good agreement between the two methods. Myocardial ischemia was responsible for a decrease in LV twist in infarct patients (P < 0.01). The decrease in LV twist was correlated with the extent of the asynergic area and global LV function as assessed by LV cineangiography (P < 0.001). Thus acute myocardial ischemia is responsible for a decrease in LV twist that is related to global LV function. Color TDE is a promising technique for straightforward assessment of LV twist in humans.
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Garot et al. (2002) conducted a case-control in Acute myocardial infarction (n=54). Anterior myocardial infarction vs. Controls was evaluated on Systolic left ventricular twist (p=<0.01). Anterior myocardial infarction was associated with a significant decrease in systolic left ventricular twist compared to controls (P<0.01), which correlated with global LV function (P<0.001).
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