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One of the most exciting recent experimental breakthroughs has been the development, by Zewail et al., of four-dimensional ultrafast electron microscopy (4D-UEM), which has the capability to combine direct spatial imaging of materials at angstrom resolution together with time resolution down to femtoseconds. We identify and discuss some of the wide-ranging future prospects for applying the 4D-UEM technique in organic solid-state chemistry, with reference to a variety of organic solids, including urea inclusion compounds, and in the study of biological materials such as ribosomes, proteins, and enzymes.
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Harris et al. (2005) studied this question.
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