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Abstract Introduction Factors shaping research attitudes among immigrant and later‐generation adults from racial and ethnic groups underrepresented in Alzheimer's disease (AD) research remain poorly understood. We examined whether migration‐related indicators were associated with research attitudes during community outreach for a preclinical AD trial. Methods At 21 outreach events in Southern California, 472 adults completed structured surveys as part of an outreach evaluation. The 7‐item Research Attitudes Questionnaire (RAQ) was administered, and scores were dichotomized at ≥ 28. Logistic regression adjusted for age, sex, education, and heritage. Results Of participants with known nativity, 83% were foreign‐born. Longer US residence was associated with higher odds of favorable research attitudes, whereas older age at immigration was associated with lower odds. Primary language was not independently associated after adjustment. Conclusions Migration‐related factors may shape receptivity to preclinical AD research. Recruitment may require additional trust building and navigation support for adults with shorter US residence and later‐life immigration.
Salazar et al. (Mon,) studied this question.
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