Key result
Exercise-disordered breathing in patients with chronic heart failure contributes to exercise limitations and is associated with a worsening prognosis.
Ventilatory abnormalities in chronic heart failure contribute to exercise limitations and indicate a worse prognosis.
May aid risk stratification in HF exercise testing; leaves open whether targeting disordered breathing improves outcomes.
Patients with heart failure develop various ventilatory abnormalities, including reduced ventilatory reserves, increased ventilatory demands, and high work and cost of breathing. They tend to breathe with a rapid-shallow pattern, have low end-expiratory lung volumes, and may develop rhythmic oscillations in ventilation and tidal volume. These abnormalities likely contribute to exercise limitations and are associated with a worsening prognosis.
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Olson et al. (2006) conducted a review in Chronic Heart Failure. Exercise-disordered breathing was evaluated. Exercise-disordered breathing in patients with chronic heart failure contributes to exercise limitations and is associated with a worsening prognosis.