Key result
A 54-year-old man paradoxically developed an acute ischemic stroke during the initial phase of anticoagulation therapy for a left ventricular thrombus, suggesting a risk of thrombus fragmentation.
Why the study?
Anticoagulation is essential to prevent systemic thromboembolism when an LV thrombus is detected, but paradoxically acute ischemic stroke can still occur during treatment.
Case Report (n=1)
No
This case highlights the paradoxical risk of acute ischemic stroke due to thrombus fragmentation during the initial phase of anticoagulation therapy for a left ventricular thrombus.
May warrant monitoring for early embolization in LV thrombus anticoagulation; leaves open optimal initiation strategies pending prospective data.
Left ventricular (LV) thrombus is one of complication of ischemic heart disease like acute myocardial infarction and is associated with systemic thromboembolism including ischemic stroke. If an LV thrombus is detected, anticoagulation is essential to prevent systemic thromboembolism. Paradoxically, we report a patient with acute ischemic stroke during anticoagulation treatment of LV thrombus.
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Kim et al. (2022) conducted a case report in Left ventricular thrombus (n=1). Anticoagulation (Enoxaparin and Warfarin) was evaluated. A 54-year-old man paradoxically developed an acute ischemic stroke during the initial phase of anticoagulation therapy for a left ventricular thrombus, suggesting a risk of thrombus fragmentation.
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