Older age is associated with a greater increase in circulating norepinephrine and blood pressure in response to uniform stresses compared to young subjects.
Observational
Do young subjects have a different norepinephrine and blood pressure response to stress compared to old subjects?
Age increases the sympathetic nervous system and blood pressure response to physical stress.
While at rest young subjects have lower mean arterial blood pressure than old subjects and lower circulating levels of the neurotransmitter of the sympathetic nervous system, norepinephrine (NE). After standing and performing an isometric exercise, young subjects increase their circulating levels of NE less than old subjects. The cold pressor test is commonly used as a stimulus to the sympathetic nervous system, and young subjects have a much smaller pressor response than old subjects. In response to uniform stresses young subjects secrete less NE and have a smaller blood pressure response than old subjects.
Palmer et al. (1978) reported an observational. Older age vs. Young subjects was evaluated on Norepinephrine and blood pressure response to stress. Older age is associated with a greater increase in circulating norepinephrine and blood pressure in response to uniform stresses compared to young subjects.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: