The iodine content of thyroid tissue from patients with autoimmune thyroid itis was determined in 10 cases. The concentration was usually below 60 μg/g of tissue wet weight and the total content below 4000 μg. The thyroidal proteins were studied in 8 patients. In four thyroglobulin formed from 25 to 52 per cent of the thyroid proteins. Two patients who had the lowest iodine content were hypothyroid. There is a correlation between the decrease in thyroglobulin, the decrease in iodine content, and the appearance of clinical hypothyroidism.
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Kivikangas et al. (1970) studied this question.
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