Continuous Stochastic Detection of Amino Acid Enantiomers with a Protein Nanopore

A stochastic sensing method: Discrimination between enantiomeric amino acids is achieved when the amino acids bind to a CuII complex within a protein nanopore sensor, which provides a chiral environment. The potential of the method is demonstrated by real-time observation of the increase in enantiomeric excess during an enzymatic kinetic resolution. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.