Why the study?
Is obstructive sleep apnea syndrome associated with elevated serum levels of inflammatory markers, arterial stiffening, and endothelial dysfunction compared to healthy controls?
Population
18 studies pooling 736 patients with obstructive sleep apnea syndrome (OSAS) and 424 healthy persons
Comparison
Obstructive sleep apnea syndrome (OSAS) vs Healthy persons (controls)
Design
Meta-analysis
Authors
Loading...
Vascular monitoring may be warranted in moderate-severe OSAS; confirms mechanistic links via endothelial dysfunction and arterial stiffening.
Is obstructive sleep apnea syndrome associated with elevated serum levels of inflammatory markers, arterial stiffening, and endothelial dysfunction compared to healthy controls?
Obstructive sleep apnea syndrome is associated with reduced endothelial function, increased arterial stiffness, and elevated systemic inflammation, providing a mechanistic link to cardiovascular disease.
Wang et al. (2015) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: