Key result
Focal carotid plaque was present in 40% of women with SLE and independently associated with older age, higher systolic BP, higher LDL, prolonged prednisone, and prior coronary events (P<0.05).
Why the study?
What are the prevalence and risk factors for carotid atherosclerosis in women with systemic lupus erythematosus?
Population
175 women with systemic lupus erythematosus (SLE), predominantly white (87%), mean age 44.9 years.
Design
Cross-sectional
Authors
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High carotid plaque prevalence in SLE supports CV risk vigilance including steroid minimization; cross-sectional data leave causal and interventional effects open.
Cross-Sectional (n=175)
What are the prevalence and risk factors for carotid atherosclerosis in women with systemic lupus erythematosus?
p-value: p=< 0.05
In women with SLE, carotid atherosclerosis is highly prevalent (40%) and is independently associated with both traditional cardiovascular risk factors and prolonged prednisone use.
Manzi et al. (1999) conducted a cross-sectional in Systemic lupus erythematosus (n=175). Cardiovascular and SLE-specific risk factors was evaluated on Focal carotid plaque (p=< 0.05). Focal carotid plaque was present in 40% of women with SLE and independently associated with older age, higher systolic BP, higher LDL, prolonged prednisone, and prior coronary events (P<0.05).
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