Key result
Isolated single heart cells provide a valuable model for electrophysiological experiments, enabling intracellular dialysis and single-channel analysis of ionic currents.
Population
Isolated single cardiac cells (adult mammalian, embryonic, and amphibian hearts)
Design
Review
Authors
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Supports isolated cardiac cells for electrophysiological studies; leaves open clinical translation to arrhythmia care.
This review highlights the foundational techniques and advantages of using isolated single cardiac cells for electrophysiological studies, including patch-clamp and intracellular dialysis.
Hiroshi Irisawa (1984) reported a review. Isolated single heart cells provide a valuable model for electrophysiological experiments, enabling intracellular dialysis and single-channel analysis of ionic currents.
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