What question did this study set out to answer?

This research examines how efferent impulses in the splanchnic nerve react to various physiological states and chemical agents.

February 1, 1946Acta Physiologica Scandinavica

Efferent Impulses in the Splanchnic Nerve

View Full Paper

Ask AI

Bookmark

Population

Cats (preclinical model)

Comparison

Physiological and pharmacological stimuli and… vs Baseline or normal physiological conditions

Design

Preclinical

Authors

BGBo E. GernandtNational Institutes of Health GLG. LiljestrandLithuanian University of Educational Sciences YZYngve ZottermanUmeå University

Discussion

Member takes

Implication

Does not support clinical changes in hypoxia or shock management; leaves open translation of splanchnic reflexes to human autonomic control.

Key Points

This research examines how efferent impulses in the splanchnic nerve react to various physiological states and chemical agents.
Efferent impulses were recorded in the splanchnic nerve of cats under different conditions.
Responses to asphyxia, artificial respiration, and chemical injections (acetylcholine, adrenaline) were analyzed.
The impacts of carbon dioxide levels and nerve sectioning were also evaluated.
Efferent impulse amplitude increased during asphyxia and decreased with artificial respiration.
Acetylcholine injection caused a marked increase in nerve potentials, while adrenaline often diminished them.
Nerve activity significantly increased after the sectioning of sinus and vagodepressor nerves.

Structured PICO

Population

Cats (preclinical model)

Intervention

Physiological and pharmacological stimuli (asphyxia, hypoxia, hyperoxia, hypercapnia, bleeding, acetylcholine, adrenaline) and denervation of sinus and vagodepressor nerves

Comparator

Baseline or normal physiological conditions

Outcome

Efferent impulses/electric activity in the splanchnic nervesurrogate

This preclinical study demonstrates that splanchnic nerve efferent activity is reflexively modulated by chemo- and pressoreceptors in response to blood gases, blood pressure changes, and autonomic drugs.

Cite This Study

Gernandt et al. (1946) studied this question.

synapsesocial.com/papers/6a21d255d1d7fc54ffc013ce https://doi.org/10.1111/j.1748-1716.1946.tb00343.x

View Full Paper

Ask AI

Bookmark

Implication

Does not support clinical changes in hypoxia or shock management; leaves open translation of splanchnic reflexes to human autonomic control.

Efferent Impulses in the Splanchnic Nerve

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Efferent Impulses in the Splanchnic Nerve

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider