What question did this study set out to answer?

To evaluate how breathing pure oxygen alters respiration, blood pressure, and pulse rate via carotid sinus chemoreceptor mechanisms.

January 1, 1942Acta Physiologica Scandinavica

Influence of Oxygen Inhalation on the Chemo‐receptor Activity of the Sinus Region

View Full Paper

Ask AI

Bookmark

Authors

UEU. S. von EulerKarolinska University Hospital GLG. LiljestrandLithuanian University of Educational Sciences

Discussion

Member takes

Implication

Laboratory study reveals acute respiratory and cardiovascular depression following oxygen inhalation in anesthetized animals, indicating carotid chemoreceptors continuously drive basal ventilation.

Key Points

To evaluate how breathing pure oxygen alters respiration, blood pressure, and pulse rate via carotid sinus chemoreceptor mechanisms.
Substituted pure oxygen for atmospheric air in anesthetized cats and dogs.
Assessed respiratory dynamics and hemodynamic responses before and after bilateral carotid sinus denervation combined with vagodepressor nerve section.
Oxygen inhalation induced an immediate reduction in respiratory rate and depth that normalized within minutes, an effect completely abolished following bilateral sinus denervation.
Arterial blood pressure decreased by an average of 2.2% in cats during oxygen breathing, but paradoxically increased when oxygen was inhaled following sinus denervation and vagodepressor section.
Pulse rate declined by an average of 3.3% in cats during oxygen inhalation, which was largely abolished by combined sinus denervation and vagodepressor section.

Cite This Study

Euler et al. (1942) studied this question.

synapsesocial.com/papers/6a738914644e61a44f4e64f8 https://doi.org/10.1111/j.1748-1716.1942.tb01440.x

View Full Paper

Ask AI

Bookmark

Implication

Laboratory study reveals acute respiratory and cardiovascular depression following oxygen inhalation in anesthetized animals, indicating carotid chemoreceptors continuously drive basal ventilation.

Influence of Oxygen Inhalation on the Chemo‐receptor Activity of the Sinus Region

Discussion

Member takes

Implication

Key Points

Cite This Study

Influence of Oxygen Inhalation on the Chemo‐receptor Activity of the Sinus Region

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider