Key result
Isotonic beverage improves beverage hydration index by ~0.1 over water, showing greater fluid retention.
Why the study?
The study was conducted to determine the beverage hydration index and postprandial cardiac autonomic activity after consuming an isotonic beverage compared to distilled water.
Does an isotonic beverage improve fluid retention and alter cardiac autonomic activity compared to distilled water in healthy adults?
RCT (n=22)
Randomized crossover design
No
Does an isotonic beverage improve fluid retention and alter cardiac autonomic activity compared to distilled water in healthy adults?
Mean Difference: 0.1 (95% CI 0.03–0.17)
Absolute Event Rate: 1.1% vs 1%
p-value: p=0.031
Consumption of an isotonic beverage promotes greater fluid retention up to 4 hours and transiently modulates cardiac autonomic activity compared to water in healthy young adults.
This study determined the beverage hydration index (BHI) and postprandial cardiac autonomic activity after consuming an isotonic beverage (IB) compared to distilled water (DW). Twenty-two participants (50% female; mean ± SD; age, 27 ± 3 year; height, 169.1 ± 12.6 cm; weight, 73.3 ± 13.8 kg; BF%, 23 ± 10%) completed two experimental trials where they consumed 1 L DW or an IB; after which urine volume and cardiac autonomic activity was measured through 240 min. Cardiac autonomic activity was quantified using heart rate (HR), log transformed heart rate variability measures (root mean square of successive R–R intervals; RMSSD; low frequency, LF; and high frequency, HF) and systolic time intervals (pre-ejection period, PEP). BHI was significantly greater after IB consumption at min 0 (MD [95% CI]; 1.31 [0.35, 2.27]), 180 min (0.09 [0.022, 0.16]), and 240 min (0.1 [0.03, 0.17]) compared to DW (p = 0.031). Net fluid balance was significantly greater in IB than DW at 180 min (90 [−16.80, 196.81]) and 240 min (106 [−13.88, 225.88]) (p = 0.037). HR decreased over time in both beverage trials but was higher following IB ingestion at 0 min (3.9 [−2.42, 10.22]), 30 min (5.3 [−0.94, 11.54]), and 60 min (2.7 [−3.42, 8.82]) (p = 0.0002). lnHF was greater 30 min post DW ingestion compared to IB (0.45 [−0.23, 1.13]) (p = 0.039). IB promotes greater fluid retention capacity compared to DW within 4 hours of consumption. The variations in cardiac autonomic measures may warrant further investigation in clinical populations (i.e., patients with autonomic failure).
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Bechke et al. (2022) conducted an RCT in Healthy adults (n=22). Isotonic beverage vs. Distilled water 1 L orally over 30 minutes was evaluated on Beverage hydration index (BHI) at 240 minutes (MD 0.1, 95% CI 0.03-0.17, p=0.031). An isotonic beverage significantly increased the beverage hydration index at 240 minutes compared to distilled water (MD 0.1, 95% CI 0.03-0.17, p=0.031), indicating greater fluid retention.
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